You’ll wonder how you ever treated acromegaly before PALSONIFY

The first and only once-daily oral with biochemical and symptom control in adults with acromegaly1*

First line1

Approved for treatment-naïve patients and patients switching from iSRLs

Fast acting1

Lowered IGF-1 in 2 to 4 weeks

Reduces symptom severity1

Reduced the severity of common acromegaly symptoms

Acromegaly control. Finally, in a pill.1

  • *PALSONIFY is approved for the treatment of adults with acromegaly who had an inadequate response to surgery and/or for whom surgery is not an option.1
  • PALSONIFY demonstrated numerically lower severity of symptom scores associated with acromegaly vs placebo, as measured by a patient-reported symptom severity tool.1
  • IGF-1=insulin-like growth factor 1; iSRLs=injected somatostatin receptor ligands.

MOA AND DOSING

Designed for SST2 specificity and oral administration1

PALSONIFY is the first and only nonpeptide SST2-selective agonist in a once-daily oral formulation. It was engineered to provide biochemical and symptom control with the convenience of once-daily dosing.1,2

  • MOA=mechanism of action; SST2=somatostatin receptor subtype 2.
image of hand holding PALSONIFY pill.
Megan: patient living with acromegaly.

Megan,

taking PALSONIFY

EFFICACY AND SAFETY

Acromegaly control across a range of patients1

In patients switching from iSRLs and those who were biochemically uncontrolled, including treatment naïve, PALSONIFY provided rapid, reliable, and sustained biochemical and symptom control—all with a low discontinuation rate.1,3

PALSONIFY national broadcast

The Only Once-Daily Acromegaly Treatment

Listen to experts in endocrinology discuss clinical evidence and insights on PALSONIFY for the treatment of acromegaly.

Palsonify national broadcast video.